Evaluation Of Bacteriuria in Benign Prostatic Hyperplasia (BPH) Among Male Patients Attending Tertiary Hospitals in Edo State, Nigeria

Abstract

Benign Prostate Hyperplasia (BPH) is a non-malignant condition characterized by the proliferation of prostate cell leading to an increase in prostate size, urethral obstruction and lower urinary tract symptoms, usually around old age due to lower urinary tract symptoms. This study is to determine the aetiological agent and antibiotics sensitivity pattern of organism responsible for bacteriuria in BPH male patients attending Central Hospital and University of Benin Teaching Hospital (UBTH), as tertiary hospitals in Edo State. Structured questionnaires were provided and urine samples were collected, spin and the deposit were used for culture, biochemical and antibiotic sensitivity test. Out of the 340 urine samples examined, 124 (36.5%) patients were positive with BPH. The high frequency among isolates observed was Escherichia coli 55(16.1%). The age of the patients was strongly associated with the prevalence of the infection (P- 0.058) while the study areas and residence of the patients were not significantly (p > 0.05) associated with the infection. However, the difference between isolates and susceptibility pattern was strongly statistically associated (p < 0.05). Conclusively, the study found no statistical relationships between socio demographic of participants and bacteriuria among BPH patients attending tertiary heath facilities in Edo State; however, the rate of antibiotic resistance to most of the isolates in our findings is worrisome for antibiotic stewardship